We are using perpetual licenses for VMware Horizon and would like to switch to the new subscription-based licensing. Is this possible?

Yes, it is possible to switch to subscription licenses. VMware offers special SKUs for this purpose within an upgrade program. These upgrade SKUs can be used by all customers of perpetual licenses with an active Subscription and Support (SnS) contract. The change is possible at the time of the renewal of the SnS contract.